ABSTRACT
Angiosarcoma is a highly malignant vascular tumor with an incidence of approximately one per ten million. There are three clinical variants; primary angiosarcoma, which occurs on the head and neck in the elderly; angiosarcoma in areas of chronic lymphedema; and post-irradiation angiosarcoma. Primary angiosarcoma shows variable-sized erythematous to violaceous nodules or plaques that become confluent as the lesion progress. We report a case of primary angiosarcoma of the scalp in a 76-year-old man with focal alopecia. Additional immunohistochemical stains showed perifollicular CD34 dominance, which suggested hair follicle-targeted carcinogenesis.
Subject(s)
Aged , Humans , Alopecia , Coloring Agents , Hair , Head , Hemangiosarcoma , Incidence , Neck , ScalpABSTRACT
Kaposi's sarcoma (KS) is a multifocal, systemic tumor of an endothelial cell origin and there are four clinical subtypes. Among these clinical subtypes, KS associated with immunosuppressive therapy mainly develops in organ transplant patients as well as in other patients who are receiving immunosuppressants for other reasons. It can occur from 1 month to more than 10 years after starting the agent and it seems to depend on the dose and type of the drug taken. We report here on a case of diffuse cutaneous iatrogenic Kaposi's sarcoma that was associated with 2 years of oral corticosteroid therapy. The patient's disease was present as various forms of cutaneous lesions without any systemic involvement.
Subject(s)
Humans , Endothelial Cells , Immunosuppressive Agents , Sarcoma, Kaposi , TransplantsABSTRACT
Subacute radiation dermatitis is a cutaneous disorder that occurs secondary to radiation exposure. It occurs after weeks to a few months from radiation exposure. Histologically, subacute radiation dermatitis presents with interface dermatitis that resembles graft-versus-host disease or a fixed drug eruption. The previous reports on this disease have usually been related to extensive or repeated coronary angiography. Herein, we report on a case of subacute radiation dermatitis that occurred 5 weeks after cardiac intervention therapy.
Subject(s)
Coronary Angiography , Dermatitis , Drug Eruptions , Fluoroscopy , Graft vs Host DiseaseABSTRACT
Candida albicans is a dimorphic yeast which is responsible for 70 percent to 80 percent of all candidial infection, and is the most common cause of superficial and systemic candidiasis. Invasive candidiasis occurs under certain circumstances such as immunosuppression, prolonged hospitalization, and previous antibiotics use. We report a case of candidiasis with a unusual presentation of subcutaneous abscess. A 54 year-old woman came to our clinic with painful erythematous swelling plaques and nodules on the face and arms. She was hospitalized with generalized edema and weakness of both leg. She had a history of herbal medication for 1 year and was finally diagnosed with iatrogenic Cushing syndrome in department of the endocrinology. Biopsy of the lesion revealed chronic inflammation in dermis and subcutis and budding yeasts with pseudohyphae were shown in Gomoris Methenamine silver stain. And Candida albicans was identified by fungus culture.
Subject(s)
Female , Humans , Abscess , Anti-Bacterial Agents , Arm , Biopsy , Candida albicans , Candidiasis , Candidiasis, Invasive , Cushing Syndrome , Dermis , Edema , Endocrinology , Fungi , Hospitalization , Immunosuppression Therapy , Inflammation , Leg , Methenamine , Porphyrins , Saccharomycetales , YeastsABSTRACT
Livedoid vasculopathy is a chronic disease which appears with recurrent painful livedo reticularis patches and ulcers. The exact cause is unknown but it is known to be associated with some connective tissue or infectious diseases. Vasculopathy has been frequently reported as a cutaneous manifestation in chronic hepatitis C patients. As research into the pathology of hepatitis C progresses, new relationships between it and skin symptoms are emerging. We report a 44-year-old woman with livedoid vasculopathy who has no other known associated disease but chronic hepatitis C.
Subject(s)
Adult , Female , Humans , Chronic Disease , Communicable Diseases , Connective Tissue , Hepatitis , Hepatitis C , Hepatitis C, Chronic , Livedo Reticularis , Skin , UlcerABSTRACT
Acute generalized exanthematous pustulosis is a skin reaction characterized by an acute onset, fever, and a cutaneous eruption with non-follicular sterile pustules on edematous erythema. It mimics many of the features of pustular psoriasis but is differentiated by its characteristic clinical course and history. The cause is usually ingested drugs. We report a case of acute generalized exanthematous pustulosis possibly induced by ritodrine